Opioid Analgesics for adults Class II

  • titrate to individual response
  • dose does not apply to patients with renal or hepatic insufficiency
  • Morphine
    • Immediate release (MSIR): tab 15, 30 mg. Dose: 5-30 mg q2-6h
    • MS Contin, Oramorph SR: Tab: 15, 30, 60, 100 mg. Dose 15-120 mg q12
    • Roxanol SR: 30 mg. Dose 30 mg q8 prn
    • Usual parenteral dose: 5-10 mg q4-5h
  • Hydromorphone (Dilaudid)
    • Tab: 2, 4, 8 mg. Dose: 2-6 mg po q3-4h
    • 3 mg rectal suppository
    • Usual parental dose: 1.5 mg q3-4h
  • Levorphanol (Levo-Dromoran)
    • Oral: 4 mg q6-8h
    • Usual parental dose: 2 mg q6-8h
  • Meperidine (Demerol)
    • Oral dose not recommended
    • Usual parenteral dose: 50-100 mg q3h, extreme caution if patient has renal failure, accumulation of active metabolite may cause CNS excitement & seizure
  • Methadone (Dolophine)
    • Comes in 5, 10 mg
    • Oral: 5-20 mg q6-8h
    • Usual parenteral dose: 10 mg q6-8h
  • Oxycodone
    • Roxicodone: soln: 5 mg/5ml, 20 mg/ml, tab 5 mg. Dose: 5-10 mg q3-4h
    • Oxycontin controlled release tab: 10, 20, 40,  80, 160 mg. Dose variable
    • Parenteral: not available
  • Oxymorphone (Numorphan)
    • Oral: not available
    • Usual parenteral dose: 1 mg q3-4h
Further Reading

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