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| Antidepressants in a
nutshell |
Prozac
- 20 mg qd
- Generic cost $0.5/pill
- SSRI, long half life
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Lexapro
- 10 mg qd, then 20 mg qd
- Cost $2/pill
- SSRI
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Wellbutrin
- Wellbutrin XL 24 hour 150 mg qd, up to 300 mg qd.
cost $3/pill
- Generic Bupropion HCl 12 hour tablets 150MG. cost
$1/pill
- Dopamine reuptake inhibitor
- May cause agitation, insomnia. Avoid if history of psychosis.
- Also used for smoking cessation.
- May increase risk for seizure, especially dose >450mg/day
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Effexor XR
- 75 mg qd, up to 225 mg qd
- About $3/capsule
- May help anxiety
- Inhibits reuptake of Serotonin, Norepinephrine; to a lesser extent
dopamine.
- At doses > 200 mg per day, may increase blood pressure
- Discontinuation syndrome may occur with abrupt
discontinuation
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Nirtazapine (Remeron)
- 15 mg hs, up to 45 mg hs
- Generic available, about $1 per pill
- Antagonizes 5HT2, 5HT3 and adrenergic alpha2 receptors
- May cause sedation, weight gain.
- No
anticholinergic, adrenergic, and serotonin-related side effects
- Does not cause sexual dysfunction, orthostatic
hypotension.
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Selective Serotonin Reuptake Inhibitor
Psychiatric disorder info center
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